Δημοσιεύτηκε στις Jun 5, 2021

Ιάκωβος Σούσης Μαιευτήρας-Γυναικολόγος, Ιατρός Αναπαραγωγής

COVID19 associated with adverse maternal and neonatal outcomes

After analysing a cohort of pregnant women at the time of birth, researchers have found that women with SARS-CoV-2 infection were more than twice as likely to have foetal death or preterm birth than non-infected women.

The study, published in the American Journal of Obstetrics and Gynecology, included 342,080 women, of whom 3,527 had laboratory-confirmed SARS-CoV-2 infection. Younger women of non-white ethnicity, primiparous, residing in the most deprived areas, or with comorbidities were more likely to have SARS-CoV-2 infection.

The researchers compared maternal and perinatal outcomes between infected versus non-infected women.

The results show that SARS-CoV-2-infected women had higher rates of foetal death and preterm birth, increased risks of preeclampsia/eclampsia and emergency caesarean delivery, and prolonged admission following birth. There were no significant differences in other outcomes, including small for gestational age infant, induction of labour, or instrumental vaginal delivery.

The observed increase in rates of adverse neonatal outcomes was attributed to increased preterm birth, but the researchers were not able to stratify preterm birth into spontaneous and clinician-initiated.

These findings should guide the counselling of pregnant women about risks of SARS-COV-2 infection and indicate that pregnant women should be prioritised for vaccination, the authors concluded.
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